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Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review

BACKGROUND: Dizziness is a common reason for consulting a general practitioner and there is a broad range of possible underlying aetiologies. There are few evidence-based data about prevalence, aetiology and prognosis in primary care. We aimed to conduct a systematic review of symptom-evaluating stu...

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Autores principales: Bösner, Stefan, Schwarm, Sonja, Grevenrath, Paula, Schmidt, Laura, Hörner, Kaja, Beidatsch, Dominik, Bergmann, Milena, Viniol, Annika, Becker, Annette, Haasenritter, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819275/
https://www.ncbi.nlm.nih.gov/pubmed/29458336
http://dx.doi.org/10.1186/s12875-017-0695-0
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author Bösner, Stefan
Schwarm, Sonja
Grevenrath, Paula
Schmidt, Laura
Hörner, Kaja
Beidatsch, Dominik
Bergmann, Milena
Viniol, Annika
Becker, Annette
Haasenritter, Jörg
author_facet Bösner, Stefan
Schwarm, Sonja
Grevenrath, Paula
Schmidt, Laura
Hörner, Kaja
Beidatsch, Dominik
Bergmann, Milena
Viniol, Annika
Becker, Annette
Haasenritter, Jörg
author_sort Bösner, Stefan
collection PubMed
description BACKGROUND: Dizziness is a common reason for consulting a general practitioner and there is a broad range of possible underlying aetiologies. There are few evidence-based data about prevalence, aetiology and prognosis in primary care. We aimed to conduct a systematic review of symptom-evaluating studies on prevalence, aetiology or prognosis of dizziness in primary care. METHODS: We systematically searched MEDLINE and EMBASE. Two independent researchers screened titles and abstracts according to predefined criteria. We included all studies evaluating the symptoms ‘dizziness’ or ‘vertigo’ as a reason for consultation in primary care. We extracted data about study population and methodology and prevalence, aetiology and prognosis. Two raters independently judged study quality and risk of bias. We investigated the variation across studies using forest plots, I(2) and prediction intervals. Since we anticipated a great amount of clinical and unexplained statistical heterogeneity, we provided qualitative syntheses instead of pooled estimates. RESULTS: We identified 31 studies (22 on prevalence, 14 on aetiology and 8 on prognosis). Consultation prevalence differs between 1,0 and 15,5%. The most common aetiologies are vestibular/peripheral (5,4-42,1%), benign peripheral positional vertigo (4,3-39,5%), vestibular neuritis (0,6-24,0%), Menière’s disease (1,4-2,7%), cardiovascular disease (3,8-56,8%), neurological disease (1,4-11,4%), psychogenic (1,8-21,6%), no clear diagnosis (0,0-80,2%). While studies based on subjective patient assessment reported improvement rates from 37 to 77%, these findings could not be confirmed when applying instruments that measure symptom severity or quality of life. CONCLUSION: There is a broad variety of possible underlying diseases for the symptom dizziness. There exist only few methodologically sound studies concerning aetiology and prognosis of dizziness. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12875-017-0695-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-58192752018-02-21 Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review Bösner, Stefan Schwarm, Sonja Grevenrath, Paula Schmidt, Laura Hörner, Kaja Beidatsch, Dominik Bergmann, Milena Viniol, Annika Becker, Annette Haasenritter, Jörg BMC Fam Pract Research Article BACKGROUND: Dizziness is a common reason for consulting a general practitioner and there is a broad range of possible underlying aetiologies. There are few evidence-based data about prevalence, aetiology and prognosis in primary care. We aimed to conduct a systematic review of symptom-evaluating studies on prevalence, aetiology or prognosis of dizziness in primary care. METHODS: We systematically searched MEDLINE and EMBASE. Two independent researchers screened titles and abstracts according to predefined criteria. We included all studies evaluating the symptoms ‘dizziness’ or ‘vertigo’ as a reason for consultation in primary care. We extracted data about study population and methodology and prevalence, aetiology and prognosis. Two raters independently judged study quality and risk of bias. We investigated the variation across studies using forest plots, I(2) and prediction intervals. Since we anticipated a great amount of clinical and unexplained statistical heterogeneity, we provided qualitative syntheses instead of pooled estimates. RESULTS: We identified 31 studies (22 on prevalence, 14 on aetiology and 8 on prognosis). Consultation prevalence differs between 1,0 and 15,5%. The most common aetiologies are vestibular/peripheral (5,4-42,1%), benign peripheral positional vertigo (4,3-39,5%), vestibular neuritis (0,6-24,0%), Menière’s disease (1,4-2,7%), cardiovascular disease (3,8-56,8%), neurological disease (1,4-11,4%), psychogenic (1,8-21,6%), no clear diagnosis (0,0-80,2%). While studies based on subjective patient assessment reported improvement rates from 37 to 77%, these findings could not be confirmed when applying instruments that measure symptom severity or quality of life. CONCLUSION: There is a broad variety of possible underlying diseases for the symptom dizziness. There exist only few methodologically sound studies concerning aetiology and prognosis of dizziness. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12875-017-0695-0) contains supplementary material, which is available to authorized users. BioMed Central 2018-02-20 /pmc/articles/PMC5819275/ /pubmed/29458336 http://dx.doi.org/10.1186/s12875-017-0695-0 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Bösner, Stefan
Schwarm, Sonja
Grevenrath, Paula
Schmidt, Laura
Hörner, Kaja
Beidatsch, Dominik
Bergmann, Milena
Viniol, Annika
Becker, Annette
Haasenritter, Jörg
Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review
title Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review
title_full Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review
title_fullStr Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review
title_full_unstemmed Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review
title_short Prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review
title_sort prevalence, aetiologies and prognosis of the symptom dizziness in primary care – a systematic review
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819275/
https://www.ncbi.nlm.nih.gov/pubmed/29458336
http://dx.doi.org/10.1186/s12875-017-0695-0
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