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Nilotinib impairs skeletal myogenesis by increasing myoblast proliferation

BACKGROUND: Tyrosine kinase inhibitors (TKIs) are effective therapies with demonstrated antineoplastic activity. Nilotinib is a second-generation FDA-approved TKI designed to overcome Imatinib resistance and intolerance in patients with chronic myelogenous leukemia (CML). Interestingly, TKIs have al...

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Detalles Bibliográficos
Autores principales:	Contreras, Osvaldo, Villarreal, Maximiliano, Brandan, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819301/ https://www.ncbi.nlm.nih.gov/pubmed/29463296 http://dx.doi.org/10.1186/s13395-018-0150-5

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