Cargando…

Effects of 17β-Estradiol on Mitophagy in the Murine MC3T3-E1 Osteoblast Cell Line is Mediated via G Protein-Coupled Estrogen Receptor and the ERK1/2 Signaling Pathway

BACKGROUND: Osteoporosis is associated with 17β-estradiol deficiency. The G protein-coupled receptor 30 (GPR30) is known to be an estrogen-responsive receptor, but its role in the degradation of mitochondria in osteoblasts by autophagy, or mitophagy, remains unclear. The aim of this in vitro study w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Xiaoqi, Yang, Xuhao, Zhao, Yuyan, Li, Yinan, Guo, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819311/ https://www.ncbi.nlm.nih.gov/pubmed/29438359 http://dx.doi.org/10.12659/MSM.908705

Ejemplares similares

17β-Estradiol on the Expression of G-Protein Coupled Estrogen Receptor (GPER/GPR30) Mitophagy, and the PI3K/Akt Signaling Pathway in ATDC5 Chondrocytes In Vitro
por: Fan, Dong-xiao, et al.
Publicado: (2018)

Effect of ANGPTL7 on Proliferation and Differentiation of MC3T3-E1 Cells
por: Lu, XiaoQing, et al.
Publicado: (2019)

The Effects of Photobiomodulation on MC3T3-E1 Cells via 630 nm and 810 nm Light-Emitting Diode
por: Chang, Biao, et al.
Publicado: (2019)

Silent Mating Type Information Regulation 2 Homolog (SIRT1) Influences Osteogenic Proliferation and Differentiation of MC3T3-E1 Cells via Regulation of miR-132-3p
por: Qu, Hangbo, et al.
Publicado: (2019)

17β-Estradiol Promotes Angiogenesis of Rat Cardiac Microvascular Endothelial Cells In Vitro
por: Liu, HaiTao, et al.
Publicado: (2018)

17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway
por: Wang, Tao, et al.
Publicado: (2016)

Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells
por: Tan, Jin, et al.
Publicado: (2018)

PTEN-Induced Putative Kinase 1 (PINK1)/Parkin-Mediated Mitophagy Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity
por: Zhang, Yao, et al.
Publicado: (2019)

Bcl-2 19-kDa Interacting Protein 3 (BNIP3)-Mediated Mitophagy Attenuates Intermittent Hypoxia-Induced Human Renal Tubular Epithelial Cell Injury
por: Zhang, Xiao-Bin, et al.
Publicado: (2022)

To Explore the Protective Mechanism of PTEN-Induced Kinase 1 (PINK1)/Parkin Mitophagy-Mediated Extract of Periplaneta Americana on Lipopolysaccharide-Induced Cardiomyocyte Injury
por: Li, Jie, et al.
Publicado: (2019)

Probucol Protects Against Contrast-Induced Acute Kidney Injury via the Extracellular Signal-Regulated Kinases 1 and 2 (ERK1/2)/JNK-Caspase 3 Pathway in Diabetic Rats
por: Ma, Xingxing, et al.
Publicado: (2019)

N-myc Downstream-Regulated Gene 2 (NDRG2) Promotes Bone Morphogenetic Protein 2 (BMP2)-Induced Osteoblastic Differentiation and Calcification by Janus Kinase 3 (JAK3)/Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway
por: Chen, SunYu, et al.
Publicado: (2020)

Sesamin Promotes Osteoblastic Differentiation and Protects Rats from Osteoporosis
por: Ma, Zhong-ping, et al.
Publicado: (2019)

Zingerone Promotes Osteoblast Differentiation Via MiR-200c-3p/smad7 Regulatory Axis in Human Bone Mesenchymal Stem Cells
por: Song, Yuxi, et al.
Publicado: (2020)

EXT1, Regulated by MiR-665, Promotes Cell Apoptosis via ERK1/2 Signaling Pathway in Acute Lymphoblastic Leukemia
por: Liu, Na-wei, et al.
Publicado: (2019)

Hirudin Protects Ang II-Induced Myocardial Fibroblasts Fibrosis by Inhibiting the Extracellular Signal-Regulated Kinase1/2 (ERK1/2) Pathway
por: Yu, Chunxia, et al.
Publicado: (2018)

Helicobacter Pylori Induces GATA3-Dependent Chitinase 3 Like 1 (CHI3L1) Upregulation and Contributes to Vascular Endothelial Injuries
por: Chi, Jingshu, et al.
Publicado: (2019)

Aminoacylase 1 (ACY-1) Mediates the Proliferation and Migration of Neuroblastoma Cells in Humans Through the ERK/Transforming Growth Factor β (TGF-β) Signaling Pathways
por: Chen, Zimin, et al.
Publicado: (2021)

Ginsenoside Rb1 Facilitates Browning by Repressing Wnt/β-Catenin Signaling in 3T3-L1 Adipocytes
por: Fan, Qingxin, et al.
Publicado: (2021)

Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NF-κB-PUMA Signaling
por: Yin, Qiang, et al.
Publicado: (2016)

Effects of High-Glucose and High-Fat Condition on Estrogen Receptor- and Sexual Precocity-Related Genes in GT1-7 Cells
por: Wang, Shuqin, et al.
Publicado: (2020)

Triple Negative Breast Cancer Depends on Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P)/Sphingosine 1-Phosphate Receptor 3 (S1PR3)/Notch Signaling for Metastasis
por: Wang, Shushu, et al.
Publicado: (2018)

1,25-Dihydroxyvitamin D(3) Does Not Affect MicroRNA Expression When Suppressing Human Th17 Differentiation
por: Huang, Jian, et al.
Publicado: (2017)

3,6-diazabicyclo[3.3.1]heptanes Induces Apoptosis and Arrests Cell Cycle in Prostate Cancer Cells
por: Wei, Hongjian, et al.
Publicado: (2020)

Calycosin, a Phytoestrogen Isoflavone, Induces Apoptosis of Estrogen Receptor-Positive MG-63 Osteosarcoma Cells via the Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway
por: Sun, Haitao, et al.
Publicado: (2018)

Expression of NLPR3 in Psoriasis Is Associated with Enhancement of Interleukin-1β and Caspase-1
por: Su, Fei, et al.
Publicado: (2018)

Anticancer Activity of Mukonal Against Human Laryngeal Cancer Cells Involves Apoptosis, Cell Cycle Arrest, and Inhibition of PI3K/AKT and MEK/ERK Signalling Pathways
por: Li, Liu, et al.
Publicado: (2018)

Vitamin D3 Is Transformed into 1,25(OH)(2)D(3) by Triggering CYP3A11(CYP3A4) Activity and Hydrolyzing Midazolam
por: Zhu, Hanfei, et al.
Publicado: (2019)

Costunolide Inhibits the Growth of OAW42-A Multidrug-Resistant Human Ovarian Cancer Cells by Activating Apoptotic and Autophagic Pathways, Production of Reactive Oxygen Species (ROS), Cleaved Caspase-3 and Cleaved Caspase-9
por: Fang, Yichen, et al.
Publicado: (2019)

Effects of 3-Tetrazolyl Methyl-3-Hydroxy-Oxindole Hybrid (THOH) on Cell Proliferation, Apoptosis, and G2/M Cell Cycle Arrest Occurs by Targeting Platelet-Derived Growth Factor D (PDGF-D) and the MEK/ERK Signaling Pathway in Human Lung Cell Lines SK-LU-1, A549, and A-427
por: Li, Peng, et al.
Publicado: (2018)

Kaempferol Sensitizes Human Ovarian Cancer Cells-OVCAR-3 and SKOV-3 to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis via JNK/ERK-CHOP Pathway and Up-Regulation of Death Receptors 4 and 5
por: Zhao, Yingmei, et al.
Publicado: (2017)

Estrogen Receptor Mediates the Radiosensitivity of Triple-Negative Breast Cancer Cells
por: Chen, Xingxing, et al.
Publicado: (2017)

High Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Expression Promotes Proliferation, Migration, and Invasion of Non-Small Cell Lung Cancer via ERK/Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway
por: Liu, Chang, et al.
Publicado: (2019)

Basic Fibroblast Growth Factor Reduces Permeability and Apoptosis of Human Brain Microvascular Endothelial Cells in Response to Oxygen and Glucose Deprivation Followed by Reoxygenation via the Fibroblast Growth Factor Receptor 1 (FGFR1)/ERK Pathway
por: Chen, Peng, et al.
Publicado: (2019)

Evaluation of 6-chloro-N-[3,4-disubstituted-1,3-thiazol-2(3H)-ylidene]-1,3-benzothiazol-2-amine Using Drug Design Concept for Their Targeted Activity Against Colon Cancer Cell Lines HCT-116, HCT15, and HT29
por: Zhu, Ming-Li, et al.
Publicado: (2017)

Avicularin Reduces the Expression of Mediators of Inflammation and Oxidative Stress in Bradykinin-Treated MG-63 Human Osteoblastic Osteosarcoma Cells
por: Zhang, Zhentao, et al.
Publicado: (2020)

High-Mobility Group Box 1 (HMGB1) Promotes Angiogenesis and Tumor Migration by Regulating Hypoxia-Inducible Factor 1 (HIF-1α) Expression via the Phosphatidylinositol 3-Kinase (PI3K)/AKT Signaling Pathway in Breast Cancer Cells
por: He, Honger, et al.
Publicado: (2019)

Up-Regulation of Long Noncoding RNA SRA Promotes Cell Growth, Inhibits Cell Apoptosis, and Induces Secretion of Estradiol and Progesterone in Ovarian Granular Cells of Mice
por: Li, Yan, et al.
Publicado: (2018)

Resveratrol Induces Apoptosis in Murine Prostate Cancer Cells via Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Reactive Oxygen Species (ROS)/P53 Signaling
por: Wang, Delong, et al.
Publicado: (2018)

Overexpression of the Ubiquilin-4 (UBQLN4) is Associated with Cell Cycle Arrest and Apoptosis in Human Normal Gastric Epithelial Cell Lines GES-1 Cells by Activation of the ERK Signaling Pathway
por: Huang, Shengkai, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rened0psjnimt47ltnbjuv27vq