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Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes
A substantial proportion of influenza-related childhood deaths are due to infection with influenza B viruses, which co-circulate in the human population as two antigenically distinct lineages defined by the immunodominant receptor binding protein, hemagglutinin. While broadly cross-reactive, protect...
Autores principales: | Wohlbold, Teddy John, Podolsky, Kira A., Chromikova, Veronika, Kirkpatrick, Ericka, Falconieri, Veronica, Meade, Philip, Amanat, Fatima, Tan, Jessica, tenOever, Benjamin R., Tan, Gene S., Subramaniam, Sriram, Palese, Peter, Krammer, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819343/ https://www.ncbi.nlm.nih.gov/pubmed/28827718 http://dx.doi.org/10.1038/s41564-017-0011-8 |
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