Cargando…
Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease
Mixed pathology, with both Alzheimer’s disease and vascular abnormalities, is the most common cause of clinical dementia in the elderly. While usually thought to be concurrent diseases, the fact that changes in cerebral blood flow are a prominent early and persistent alteration in Alzheimer’s diseas...
Autores principales: | Bennett, Rachel E., Robbins, Ashley B., Hu, Miwei, Cao, Xinrui, Betensky, Rebecca A., Clark, Tim, Das, Sudeshna, Hyman, Bradley T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819390/ https://www.ncbi.nlm.nih.gov/pubmed/29358399 http://dx.doi.org/10.1073/pnas.1710329115 |
Ejemplares similares
-
Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma
por: Tsou, Pei-Suen, et al.
Publicado: (2019) -
RIP1 kinase mediates angiogenesis by modulating macrophages in experimental neovascularization
por: Ueta, Takashi, et al.
Publicado: (2019) -
Childhood trauma history is linked to abnormal brain connectivity in major depression
por: Yu, Meichen, et al.
Publicado: (2019) -
Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease
por: Mano, Tatsuo, et al.
Publicado: (2017) -
Parkinson’s disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration
por: Chen, Xi, et al.
Publicado: (2019)