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STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation
The adaptor proteins STAC1, STAC2, and STAC3 represent a newly identified family of regulators of voltage-gated calcium channel (Ca(V)) trafficking and function. The skeletal muscle isoform STAC3 is essential for excitation–contraction coupling and its mutation causes severe muscle disease. Recently...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819422/ https://www.ncbi.nlm.nih.gov/pubmed/29363593 http://dx.doi.org/10.1073/pnas.1715997115 |