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High SMAD7 and p-SMAD2,3 expression is associated with environmental enteropathy in children
Enteropathies such as Crohn’s disease are associated with enteric inflammation characterized by impaired TGF-β signaling, decreased expression of phosphorylated (p)-SMAD2,3 and increased expression of SMAD7 (an inhibitor of SMAD3 phosphorylation). Environmental enteropathy (EE) is an acquired inflam...
Autores principales: | Syed, Sana, Dinallo, Vincenzo, Iqbal, Najeeha T., Di Iorio, Laura, Di Fusco, Davide, Guleria, Shan, Amadi, Beatrice C., Sadiq, Kamran, Moskaluk, Christopher, Ali, S. Asad, Kelly, Paul, Monteleone, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819826/ https://www.ncbi.nlm.nih.gov/pubmed/29415065 http://dx.doi.org/10.1371/journal.pntd.0006224 |
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