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High SMAD7 and p-SMAD2,3 expression is associated with environmental enteropathy in children

Enteropathies such as Crohn’s disease are associated with enteric inflammation characterized by impaired TGF-β signaling, decreased expression of phosphorylated (p)-SMAD2,3 and increased expression of SMAD7 (an inhibitor of SMAD3 phosphorylation). Environmental enteropathy (EE) is an acquired inflam...

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Detalles Bibliográficos
Autores principales: Syed, Sana, Dinallo, Vincenzo, Iqbal, Najeeha T., Di Iorio, Laura, Di Fusco, Davide, Guleria, Shan, Amadi, Beatrice C., Sadiq, Kamran, Moskaluk, Christopher, Ali, S. Asad, Kelly, Paul, Monteleone, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819826/
https://www.ncbi.nlm.nih.gov/pubmed/29415065
http://dx.doi.org/10.1371/journal.pntd.0006224

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