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Gli3 is a negative regulator of Tas1r3-expressing taste cells

Mouse taste receptor cells survive from 3–24 days, necessitating their regeneration throughout adulthood. In anterior tongue, sonic hedgehog (SHH), released by a subpopulation of basal taste cells, regulates transcription factors Gli2 and Gli3 in stem cells to control taste cell regeneration. Using...

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Detalles Bibliográficos
Autores principales: Qin, Yumei, Sukumaran, Sunil K., Jyotaki, Masafumi, Redding, Kevin, Jiang, Peihua, Margolskee, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819828/
https://www.ncbi.nlm.nih.gov/pubmed/29415007
http://dx.doi.org/10.1371/journal.pgen.1007058