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Cell-free synthesis of functional antibody fragments to provide a structural basis for antibody–antigen interaction
Growing numbers of therapeutic antibodies offer excellent treatment strategies for many diseases. Elucidation of the interaction between a potential therapeutic antibody and its target protein by structural analysis reveals the mechanism of action and offers useful information for developing rationa...
Autores principales: | Matsuda, Takayoshi, Ito, Takuhiro, Takemoto, Chie, Katsura, Kazushige, Ikeda, Mariko, Wakiyama, Motoaki, Kukimoto-Niino, Mutsuko, Yokoyama, Shigeyuki, Kurosawa, Yoshikazu, Shirouzu, Mikako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819829/ https://www.ncbi.nlm.nih.gov/pubmed/29462206 http://dx.doi.org/10.1371/journal.pone.0193158 |
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