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Tumor necrosis factor-α acts reciprocally with solute carrier family 26, member 3, (downregulated-in-adenoma) and reduces its expression, leading to intestinal inflammation

Solute carrier family 26, member 3 (Slc26a3), also termed downregulated-in-adenoma (DRA) is a member of the Slc26 family of anion transporters and is mutated in congenital chloride diarrhea. Our previous study demonstrated that DRA deficiency is associated with severely reduced colonic HCO(3)(−) sec...

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Detalles Bibliográficos
Autores principales: Ding, Xiangming, Li, Dongxiao, Li, Mengke, Tian, Dean, Yu, Hongbing, Yu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819926/
https://www.ncbi.nlm.nih.gov/pubmed/29286110
http://dx.doi.org/10.3892/ijmm.2017.3347