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Pin1 facilitates isoproterenol-induced cardiac fibrosis and collagen deposition by promoting oxidative stress and activating the MEK1/2-ERK1/2 signal transduction pathway in rats

Peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 (Pin1) is a member of a large superfamily of phosphorylation-dependent peptidyl-prolyl cis/trans isomerases, which not only regulates multiple targets at various stages of cellular processes, but is also involved in the pathogenesis of several...

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Detalles Bibliográficos
Autores principales:	Wu, Xian, Li, Mingjiang, Chen, Su-Qin, Li, Sha, Guo, Furong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819929/ https://www.ncbi.nlm.nih.gov/pubmed/29286102 http://dx.doi.org/10.3892/ijmm.2017.3354

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