Cargando…

Estrogen receptor-β-dependent effects of saikosaponin-d on the suppression of oxidative stress-induced rat hepatic stellate cell activation

Saikosaponin-d (SSd) is one of the major triterpenoid saponins derived from Bupleurum falcatum L., which has been reported to possess antifibrotic activity. At present, there is little information regarding the potential target of SSd in hepatic stellate cells (HSCs), which serve an important role i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Que, Renye, Shen, Yanting, Ren, Jianlin, Tao, Zhihui, Zhu, Xiaoyan, Li, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819932/ https://www.ncbi.nlm.nih.gov/pubmed/29286085 http://dx.doi.org/10.3892/ijmm.2017.3349

Ejemplares similares

Inhibition of oxidative stress and NLRP3 inflammasome by Saikosaponin-d alleviates acute liver injury in carbon tetrachloride-induced hepatitis in mice
por: Chen, Yirong, et al.
Publicado: (2020)

Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling
por: Chen, Yirong, et al.
Publicado: (2021)

Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation
por: Jiang, Hong, et al.
Publicado: (2021)

Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells
por: Chen, Ming-Feng, et al.
Publicado: (2016)

Mechanism of the effect of saikosaponin on atherosclerosis in vitro is based on the MAPK signaling pathway
por: Yang, Lin, et al.
Publicado: (2017)

Facile Synthesis of Saikosaponins
por: Wang, Ziqiang, et al.
Publicado: (2021)

Formulations, Hemolytic and Pharmacokinetic Studies on Saikosaponin a and Saikosaponin d Compound Liposomes
por: Zhang, Guo-Song, et al.
Publicado: (2015)

Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy
por: Li, Chang, et al.
Publicado: (2019)

Eupatilin Ameliorates Hepatic Fibrosis and Hepatic Stellate Cell Activation by Suppressing β-catenin/PAI-1 Pathway
por: Hu, Jinyuan, et al.
Publicado: (2023)

Purposing Saikosaponins for the treatment of COVID-19
por: Bahbah, Eshak I., et al.
Publicado: (2020)

Aquaporin 11-Dependent Inhibition of Proliferation by Deuterium Oxide in Activated Hepatic Stellate Cells
por: Lee, Phil Jun, et al.
Publicado: (2018)

Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins
por: Sui, Chun, et al.
Publicado: (2011)

Apamin suppresses biliary fibrosis and activation of hepatic stellate cells
por: Kim, Jung-Yeon, et al.
Publicado: (2017)

Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor
por: Cortes, Ernesto, et al.
Publicado: (2018)

Saikosaponin C exerts anti-HBV effects by attenuating HNF1α and HNF4α expression to suppress HBV pgRNA synthesis
por: Pan, Yanchao, et al.
Publicado: (2019)

Chemotherapeutic Potential of Saikosaponin D: Experimental Evidence
por: Manoharan, Suryaa, et al.
Publicado: (2022)

Saikosaponin-d Suppresses COX2 Through p-STAT3/C/EBPβ Signaling Pathway in Liver Cancer: A Novel Mechanism of Action
por: Ren, Mudan, et al.
Publicado: (2019)

Silymarin suppresses hepatic stellate cell activation in a dietary rat model of non-alcoholic steatohepatitis: Analysis of isolated hepatic stellate cells
por: KIM, MINA, et al.
Publicado: (2012)

MiR-34a promotes fibrosis of hepatic stellate cells via the TGF-β pathway
por: Zhang, Jie, et al.
Publicado: (2021)

20(S)- Protopanaxadiol suppresses hepatic stellate cell activation via WIF1 demethylation-mediated inactivation of the Wnt/β-catenin pathway
por: Li, Chunxue, et al.
Publicado: (2023)

Diallyl Trisulfide Suppresses Oxidative Stress-Induced Activation of Hepatic Stellate Cells through Production of Hydrogen Sulfide
por: Zhang, Feng, et al.
Publicado: (2017)

KLF10 Inhibits TGF-β-Mediated Activation of Hepatic Stellate Cells via Suppression of ATF3 Expression
por: Hwang, Soonjae, et al.
Publicado: (2023)

Putative Genes Involved in Saikosaponin Biosynthesis in Bupleurum Species
por: Lin, Tsai-Yun, et al.
Publicado: (2013)

The Role of Saikosaponins in Therapeutic Strategies for Age-Related Diseases
por: Kim, Byeong Mo
Publicado: (2018)

A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins
por: Li, Xiaojiaoyang, et al.
Publicado: (2018)

Saikosaponin D: review on the antitumour effects, toxicity and pharmacokinetics
por: Zhou, Piao, et al.
Publicado: (2021)

Antitumor Effect of Saikosaponin A on Human Neuroblastoma Cells
por: Cheng, Tan, et al.
Publicado: (2021)

Fluorofenidone affects hepatic stellate cell activation in hepatic fibrosis by targeting the TGF-β1/Smad and MAPK signaling pathways
por: Peng, Yu, et al.
Publicado: (2019)

TGF-β dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells
por: Proell, Verena, et al.
Publicado: (2007)

Inhibition of Hepatic Stellate Cell Activation Suppresses Tumorigenicity of Hepatocellular Carcinoma in Mice
por: Kang, Min-Jung, et al.
Publicado: (2021)

Saikosaponin-d Increases the Radiosensitivity of Hepatoma Cells by Adjusting Cell Autophagy
por: Tian, Yin-Di, et al.
Publicado: (2019)

Heterogeneous Composition of Voltage-Dependent K(+) Currents in Hepatic Stellate Cells
por: Lee, Dong Hyeon, et al.
Publicado: (2007)

Hepatic Stellate Cells and Hepatocarcinogenesis
por: Barry, Anna E., et al.
Publicado: (2020)

Intercellular Adhesive Structures Between Stellate Cells – An Analysis in Cultured Human Hepatic Stellate Cells
por: Imai, Katsuyuki, et al.
Publicado: (2004)

Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α
por: Zhang, Feng, et al.
Publicado: (2018)

Prevention of TGF-β-induced early liver fibrosis by a maleic acid derivative anti-oxidant through suppression of ROS, inflammation and hepatic stellate cells activation
por: Yang, Kun-Lin, et al.
Publicado: (2017)

Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1
por: Kang, Qiaohua, et al.
Publicado: (2009)

(–)-Catechin-7-O-β-d-Apiofuranoside Inhibits Hepatic Stellate Cell Activation by Suppressing the STAT3 Signaling Pathway
por: Park, Yong Joo, et al.
Publicado: (2019)

Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study
por: Li, Xiaoyu, et al.
Publicado: (2017)

TIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling
por: Park, Sang-A, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_uo1jpdp0u1bsi7cvb2dv79emg1