Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency

A 46-year-old man visited the emergency department of our hospital with a 3-day history of anal pain, hemorrhaging, and a slight fever. He had previously been diagnosed with protein C deficiency and was prescribed dabigatran, a direct oral anticoagulant. Contrast-enhanced computed tomography showed...

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Autores principales: Eso, Yuji, Yoshiji, Satoshi, Nakakubo, Yuto, Matsuura, Minoru, Seno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820038/
https://www.ncbi.nlm.nih.gov/pubmed/29033437
http://dx.doi.org/10.2169/internalmedicine.9131-17
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author Eso, Yuji
Yoshiji, Satoshi
Nakakubo, Yuto
Matsuura, Minoru
Seno, Hiroshi
author_facet Eso, Yuji
Yoshiji, Satoshi
Nakakubo, Yuto
Matsuura, Minoru
Seno, Hiroshi
author_sort Eso, Yuji
collection PubMed
description A 46-year-old man visited the emergency department of our hospital with a 3-day history of anal pain, hemorrhaging, and a slight fever. He had previously been diagnosed with protein C deficiency and was prescribed dabigatran, a direct oral anticoagulant. Contrast-enhanced computed tomography showed severe rectal wall thickening with partial defect of enhancement. In addition, sigmoidoscopy revealed a dusky purplish swollen anorectal mucosa just above the dentate line. He was diagnosed with acute anorectal thrombophlebitis, and anticoagulant therapy with heparin was initiated. To our knowledge, this is the first case report of acute anorectal thrombophlebitis caused by protein C deficiency.
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spelling pubmed-58200382018-02-22 Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency Eso, Yuji Yoshiji, Satoshi Nakakubo, Yuto Matsuura, Minoru Seno, Hiroshi Intern Med Case Report A 46-year-old man visited the emergency department of our hospital with a 3-day history of anal pain, hemorrhaging, and a slight fever. He had previously been diagnosed with protein C deficiency and was prescribed dabigatran, a direct oral anticoagulant. Contrast-enhanced computed tomography showed severe rectal wall thickening with partial defect of enhancement. In addition, sigmoidoscopy revealed a dusky purplish swollen anorectal mucosa just above the dentate line. He was diagnosed with acute anorectal thrombophlebitis, and anticoagulant therapy with heparin was initiated. To our knowledge, this is the first case report of acute anorectal thrombophlebitis caused by protein C deficiency. The Japanese Society of Internal Medicine 2017-10-16 2018-01-15 /pmc/articles/PMC5820038/ /pubmed/29033437 http://dx.doi.org/10.2169/internalmedicine.9131-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Eso, Yuji
Yoshiji, Satoshi
Nakakubo, Yuto
Matsuura, Minoru
Seno, Hiroshi
Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency
title Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency
title_full Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency
title_fullStr Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency
title_full_unstemmed Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency
title_short Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency
title_sort acute anorectal thrombophlebitis caused by a protein c deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820038/
https://www.ncbi.nlm.nih.gov/pubmed/29033437
http://dx.doi.org/10.2169/internalmedicine.9131-17
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AT matsuuraminoru acuteanorectalthrombophlebitiscausedbyaproteincdeficiency
AT senohiroshi acuteanorectalthrombophlebitiscausedbyaproteincdeficiency

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