Diagnostic Challenge in Pancreatic Sarcoidosis Using Endoscopic Ultrasonography

We herein report a 55-year-old woman who presented with erythema and bilateral hilar lymphadenopathy 4 months prior to the detection of pancreatic lesions on an ultrasound. A skin biopsy showed evidence of sarcoidosis. The largest lesion in the tail of the pancreas was hypoechoic on endoscopic ultra...

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Detalles Bibliográficos
Autores principales: Azemoto, Nobuaki, Kumagi, Teru, Koizumi, Mitsuhito, Kuroda, Taira, Yamanishi, Hirofumi, Ohno, Yoshinori, Imamura, Yoshiki, Takeshita, Eiji, Soga, Yoshiko, Ikeda, Yoshiou, Onji, Morikazu, Hiasa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820042/
https://www.ncbi.nlm.nih.gov/pubmed/29033431
http://dx.doi.org/10.2169/internalmedicine.9084-17
Descripción
Sumario:We herein report a 55-year-old woman who presented with erythema and bilateral hilar lymphadenopathy 4 months prior to the detection of pancreatic lesions on an ultrasound. A skin biopsy showed evidence of sarcoidosis. The largest lesion in the tail of the pancreas was hypoechoic on endoscopic ultrasonography (EUS). The lesion was initially iso-enhanced on contrast enhanced-EUS (CE-EUS) but subsequently became hypoenhanced. The lesion revealed heterogeneous components of both soft and hard tissue on EUS elastography. She was ultimately diagnosed with pancreatic sarcoidosis based on the presence of noncaseating granulomas seen on pancreatic tissue retrieved through an EUS-guided fine needle aspiration biopsy.

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