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VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis

The hexameric AAA ATPase VPS4 facilitates ESCRT III filament disassembly on diverse intracellular membranes. ESCRT III components and VPS4 have been localized to the ciliary transition zone and spindle poles and reported to affect centrosome duplication and spindle pole stability. How the canonical...

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Detalles Bibliográficos
Autores principales: Ott, Carolyn, Nachmias, Dikla, Adar, Shai, Jarnik, Michal, Sherman, Shachar, Birnbaum, Ramon Y., Lippincott-Schwartz, Jennifer, Elia, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820263/
https://www.ncbi.nlm.nih.gov/pubmed/29463826
http://dx.doi.org/10.1038/s41598-018-21491-x