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VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis
The hexameric AAA ATPase VPS4 facilitates ESCRT III filament disassembly on diverse intracellular membranes. ESCRT III components and VPS4 have been localized to the ciliary transition zone and spindle poles and reported to affect centrosome duplication and spindle pole stability. How the canonical...
Autores principales: | Ott, Carolyn, Nachmias, Dikla, Adar, Shai, Jarnik, Michal, Sherman, Shachar, Birnbaum, Ramon Y., Lippincott-Schwartz, Jennifer, Elia, Natalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820263/ https://www.ncbi.nlm.nih.gov/pubmed/29463826 http://dx.doi.org/10.1038/s41598-018-21491-x |
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