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Pentose Phosphate Shunt Modulates Reactive Oxygen Species and Nitric Oxide Production Controlling Trypanosoma cruzi in Macrophages

Metabolism provides substrates for reactive oxygen species (ROS) and nitric oxide (NO) generation, which are a part of the macrophage (Mφ) anti-microbial response. Mφs infected with Trypanosoma cruzi (Tc) produce insufficient levels of oxidative species and lower levels of glycolysis compared to cla...

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Detalles Bibliográficos
Autores principales:	Koo, Sue-jie, Szczesny, Bartosz, Wan, Xianxiu, Putluri, Nagireddy, Garg, Nisha Jain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820298/ https://www.ncbi.nlm.nih.gov/pubmed/29503646 http://dx.doi.org/10.3389/fimmu.2018.00202

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