Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults

Human coronavirus (HCoV) is a known cause of influenza‐like illness (ILI). In a multisite, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12% of subjects were PCR‐positive for HCoV. The distribution of species was as follows: HCoV‐OC43 (34%), HCoV‐229E (28%)...

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Autores principales: Bouvier, Monique, Chen, Wei‐Ju, Arnold, John C., Fairchok, Mary P., Danaher, Patrick J., Lalani, Tahaniyat, Malone, Leslie, Mor, Deepika, Ridoré, Michelande, Burgess, Timothy H., Millar, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Short Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820427/
https://www.ncbi.nlm.nih.gov/pubmed/29350887
http://dx.doi.org/10.1111/irv.12538
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author Bouvier, Monique
Chen, Wei‐Ju
Arnold, John C.
Fairchok, Mary P.
Danaher, Patrick J.
Lalani, Tahaniyat
Malone, Leslie
Mor, Deepika
Ridoré, Michelande
Burgess, Timothy H.
Millar, Eugene V.
author_facet Bouvier, Monique
Chen, Wei‐Ju
Arnold, John C.
Fairchok, Mary P.
Danaher, Patrick J.
Lalani, Tahaniyat
Malone, Leslie
Mor, Deepika
Ridoré, Michelande
Burgess, Timothy H.
Millar, Eugene V.
author_sort Bouvier, Monique
collection PubMed
description Human coronavirus (HCoV) is a known cause of influenza‐like illness (ILI). In a multisite, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12% of subjects were PCR‐positive for HCoV. The distribution of species was as follows: HCoV‐OC43 (34%), HCoV‐229E (28%), HCoV‐NL63 (22%), and HCoV‐HKU1 (16%). We did not observe species‐specific differences in the clinical characteristics of HCoV infection, with the exception of HCoV‐HKU1, for which the severity of gastrointestinal symptoms trended higher on the fourth day of illness.
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spelling pubmed-58204272018-03-01 Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults Bouvier, Monique Chen, Wei‐Ju Arnold, John C. Fairchok, Mary P. Danaher, Patrick J. Lalani, Tahaniyat Malone, Leslie Mor, Deepika Ridoré, Michelande Burgess, Timothy H. Millar, Eugene V. Influenza Other Respir Viruses Short Articles Human coronavirus (HCoV) is a known cause of influenza‐like illness (ILI). In a multisite, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12% of subjects were PCR‐positive for HCoV. The distribution of species was as follows: HCoV‐OC43 (34%), HCoV‐229E (28%), HCoV‐NL63 (22%), and HCoV‐HKU1 (16%). We did not observe species‐specific differences in the clinical characteristics of HCoV infection, with the exception of HCoV‐HKU1, for which the severity of gastrointestinal symptoms trended higher on the fourth day of illness. John Wiley and Sons Inc. 2018-02-02 2018-03 /pmc/articles/PMC5820427/ /pubmed/29350887 http://dx.doi.org/10.1111/irv.12538 Text en © 2018 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Articles
Bouvier, Monique
Chen, Wei‐Ju
Arnold, John C.
Fairchok, Mary P.
Danaher, Patrick J.
Lalani, Tahaniyat
Malone, Leslie
Mor, Deepika
Ridoré, Michelande
Burgess, Timothy H.
Millar, Eugene V.
Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults
title Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults
title_full Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults
title_fullStr Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults
title_full_unstemmed Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults
title_short Species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults
title_sort species‐specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults
topic Short Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820427/
https://www.ncbi.nlm.nih.gov/pubmed/29350887
http://dx.doi.org/10.1111/irv.12538
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