Developments in the management of advanced soft-tissue sarcoma – olaratumab in context

Lartruvo(®) (olaratumab) is a fully human immunoglobulin G subclass 1 (IgG1) monoclonal antibody that inhibits platelet-derived growth factor receptor alpha (PDGFRα). The antitumor activity of olaratumab has been tested in vitro and in vivo, and inhibition of tumor growth has been observed in cancer...

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Detalles Bibliográficos
Autores principales: Moroncini, Gianluca, Maccaroni, Elena, Fiordoliva, Ilaria, Pellei, Chiara, Gabrielli, Armando, Berardi, Rossana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820470/
https://www.ncbi.nlm.nih.gov/pubmed/29497315
http://dx.doi.org/10.2147/OTT.S127609

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