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Detection of a Peptide Biomarker by Engineered Yeast Receptors
[Image: see text] Directed evolution of membrane receptors is challenging as the evolved receptor must not only accommodate a non-native ligand, but also maintain the ability to transduce the detection of the new ligand to any associated intracellular components. The G-protein coupled receptor (GPCR...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820653/ https://www.ncbi.nlm.nih.gov/pubmed/29366326 http://dx.doi.org/10.1021/acssynbio.7b00410 |