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En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse

Giant cell tumors (GCTs) are rare, benign, and locally aggressive primary bone neoplasms. Spine is seldom affected, especially above the level of sacrum. In this report, we describe a case with GCT of the cervical vertebrae which causes collapse of the corpus. A 32-year-old female presented with gra...

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Autores principales: Afsoun, Seddighi, Saied, Seddighi Amir, Amir, Nikouei, Hamed, Javadian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820874/
https://www.ncbi.nlm.nih.gov/pubmed/29492149
http://dx.doi.org/10.4103/1793-5482.181136
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author Afsoun, Seddighi
Saied, Seddighi Amir
Amir, Nikouei
Hamed, Javadian
author_facet Afsoun, Seddighi
Saied, Seddighi Amir
Amir, Nikouei
Hamed, Javadian
author_sort Afsoun, Seddighi
collection PubMed
description Giant cell tumors (GCTs) are rare, benign, and locally aggressive primary bone neoplasms. Spine is seldom affected, especially above the level of sacrum. In this report, we describe a case with GCT of the cervical vertebrae which causes collapse of the corpus. A 32-year-old female presented with gradual neck pain and abrupt paresthesia of the left hand. Computed tomography scan showed C6 vertebral collapse and magnetic resonance imaging demonstrated vertebral plana of C6 by a low signal intensity lesion on T1- and T2-weighted images. Emergent surgical intervention was taken due to the possibility of spinal injury. The tumor was removed by en-bloc resection and histopathological investigation confirmed GCT. In most of the cases, en-bloc resection of GCTs of the spine is not feasible. Despite the location and close contact of the lesion with spinal cord, later approach was successful for our case; thus, appropriate differential diagnosis for vertebral column lesions as well as selecting an optimum treatment is mandatory.
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spelling pubmed-58208742018-02-28 En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse Afsoun, Seddighi Saied, Seddighi Amir Amir, Nikouei Hamed, Javadian Asian J Neurosurg Case Report Giant cell tumors (GCTs) are rare, benign, and locally aggressive primary bone neoplasms. Spine is seldom affected, especially above the level of sacrum. In this report, we describe a case with GCT of the cervical vertebrae which causes collapse of the corpus. A 32-year-old female presented with gradual neck pain and abrupt paresthesia of the left hand. Computed tomography scan showed C6 vertebral collapse and magnetic resonance imaging demonstrated vertebral plana of C6 by a low signal intensity lesion on T1- and T2-weighted images. Emergent surgical intervention was taken due to the possibility of spinal injury. The tumor was removed by en-bloc resection and histopathological investigation confirmed GCT. In most of the cases, en-bloc resection of GCTs of the spine is not feasible. Despite the location and close contact of the lesion with spinal cord, later approach was successful for our case; thus, appropriate differential diagnosis for vertebral column lesions as well as selecting an optimum treatment is mandatory. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5820874/ /pubmed/29492149 http://dx.doi.org/10.4103/1793-5482.181136 Text en Copyright: © 2018 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Afsoun, Seddighi
Saied, Seddighi Amir
Amir, Nikouei
Hamed, Javadian
En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse
title En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse
title_full En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse
title_fullStr En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse
title_full_unstemmed En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse
title_short En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse
title_sort en-bloc resection of a giant cell tumor causing cervical vertebral collapse
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820874/
https://www.ncbi.nlm.nih.gov/pubmed/29492149
http://dx.doi.org/10.4103/1793-5482.181136
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