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Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis

BACKGROUND: The aim of this study was to identify the predictors of deterioration in sagittal balance in patients with adult scoliosis following long fusion arthrodesis to L5. MATERIAL/METHODS: A retrospective clinical study included 63 patients with adult scoliosis who underwent long fusion arthrod...

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Autores principales: Gao, Xianda, Wang, Linfeng, Yan, Changzhi, Gao, Yanlong, Shen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821000/
https://www.ncbi.nlm.nih.gov/pubmed/29442100
http://dx.doi.org/10.12659/MSM.908155
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author Gao, Xianda
Wang, Linfeng
Yan, Changzhi
Gao, Yanlong
Shen, Yong
author_facet Gao, Xianda
Wang, Linfeng
Yan, Changzhi
Gao, Yanlong
Shen, Yong
author_sort Gao, Xianda
collection PubMed
description BACKGROUND: The aim of this study was to identify the predictors of deterioration in sagittal balance in patients with adult scoliosis following long fusion arthrodesis to L5. MATERIAL/METHODS: A retrospective clinical study included 63 patients with adult scoliosis who underwent long fusion arthrodesis to L5, between February 2005 and May 2015. Radiological imaging values included the angle of lumbar lordosis (LL), and the angle of pelvic incidence (PI). The patients were divided into two cohorts, according to the threshold of average loss of sagittal vertical axis (SVA): a cohort with stable sagittal balance (SSB) and a cohort with deteriorated sagittal balance (DSB). Multivariate logistic regression analysis and the receiver operating characteristic (ROC) curve were used to identify the predictors of clinical outcome. RESULTS: There were significant differences between the SSB and DSB cohorts in age (p<0.001), preoperative SVA (p<0.001), last follow-up SVA (p<0.001), preoperative LL (p=0.001), last follow-up LL (p<0.001), subsequent L5–S1 disc degeneration (p<0.001) and PI (p=0.028). Patient age >61.5 years (OR=1.251, 95% CI, 1.055–1.484) (P=0.010), preoperative SVA >3.54 cm (OR=1.844, 95% CI, 1.249–2.732) (P=0.002) and preoperative LL <19.0 degrees (OR=0.922, 95% CI, 0.869–0.979) (P=0.008) were identified as predictors of deterioration in sagittal balance. CONCLUSIONS: Deterioration in sagittal balance following long fusion arthrodesis to L5 in patients with adult scoliosis was associated with subsequent L5–S1 disc degeneration and loss of LL, age >61.5 years, preoperative SVA >3.54 cm, and preoperative LL <19.0 degrees.
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spelling pubmed-58210002018-02-26 Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis Gao, Xianda Wang, Linfeng Yan, Changzhi Gao, Yanlong Shen, Yong Med Sci Monit Clinical Research BACKGROUND: The aim of this study was to identify the predictors of deterioration in sagittal balance in patients with adult scoliosis following long fusion arthrodesis to L5. MATERIAL/METHODS: A retrospective clinical study included 63 patients with adult scoliosis who underwent long fusion arthrodesis to L5, between February 2005 and May 2015. Radiological imaging values included the angle of lumbar lordosis (LL), and the angle of pelvic incidence (PI). The patients were divided into two cohorts, according to the threshold of average loss of sagittal vertical axis (SVA): a cohort with stable sagittal balance (SSB) and a cohort with deteriorated sagittal balance (DSB). Multivariate logistic regression analysis and the receiver operating characteristic (ROC) curve were used to identify the predictors of clinical outcome. RESULTS: There were significant differences between the SSB and DSB cohorts in age (p<0.001), preoperative SVA (p<0.001), last follow-up SVA (p<0.001), preoperative LL (p=0.001), last follow-up LL (p<0.001), subsequent L5–S1 disc degeneration (p<0.001) and PI (p=0.028). Patient age >61.5 years (OR=1.251, 95% CI, 1.055–1.484) (P=0.010), preoperative SVA >3.54 cm (OR=1.844, 95% CI, 1.249–2.732) (P=0.002) and preoperative LL <19.0 degrees (OR=0.922, 95% CI, 0.869–0.979) (P=0.008) were identified as predictors of deterioration in sagittal balance. CONCLUSIONS: Deterioration in sagittal balance following long fusion arthrodesis to L5 in patients with adult scoliosis was associated with subsequent L5–S1 disc degeneration and loss of LL, age >61.5 years, preoperative SVA >3.54 cm, and preoperative LL <19.0 degrees. International Scientific Literature, Inc. 2018-02-14 /pmc/articles/PMC5821000/ /pubmed/29442100 http://dx.doi.org/10.12659/MSM.908155 Text en © Med Sci Monit, 2018 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Gao, Xianda
Wang, Linfeng
Yan, Changzhi
Gao, Yanlong
Shen, Yong
Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis
title Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis
title_full Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis
title_fullStr Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis
title_full_unstemmed Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis
title_short Predictors of Deterioration in Sagittal Balance Following Long Fusion Arthrodesis to L5 in Patients with Adult Scoliosis
title_sort predictors of deterioration in sagittal balance following long fusion arthrodesis to l5 in patients with adult scoliosis
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821000/
https://www.ncbi.nlm.nih.gov/pubmed/29442100
http://dx.doi.org/10.12659/MSM.908155
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