Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision

Membrane lipid composition is central to the highly specialized functions of neurological tissues. In the retina, abnormal lipid metabolism causes severe forms of blindness, often through poorly understood neuronal cell death. Here, we demonstrate that deleting the de novo lipogenic enzyme fatty aci...

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Detalles Bibliográficos
Autores principales: Rajagopal, Rithwick, Zhang, Sheng, Wei, Xiaochao, Doggett, Teresa, Adak, Sangeeta, Enright, Jennifer, Shah, Vaishali, Ling, Guoyu, Chen, Shiming, Yoshino, Jun, Hsu, Fong-Fu, Semenkovich, Clay F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821215/
https://www.ncbi.nlm.nih.gov/pubmed/29321376
http://dx.doi.org/10.1172/jci.insight.97076

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