IL-7 treatment augments and prolongs sepsis-induced expansion of IL-10-producing B lymphocytes and myeloid-derived suppressor cells

Immunological dysregulation in sepsis is associated with often lethal secondary infections. Loss of effector cells and an expansion of immunoregulatory cell populations both contribute to sepsis-induced immunosuppression. The extent and duration of this immunosuppression are unknown. Interleukin 7 (...

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Detalles Bibliográficos
Autores principales: Kulkarni, Upasana, Herrmenau, Christoph, Win, Stephanie J., Bauer, Michael, Kamradt, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821326/
https://www.ncbi.nlm.nih.gov/pubmed/29466409
http://dx.doi.org/10.1371/journal.pone.0192304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821326/
https://www.ncbi.nlm.nih.gov/pubmed/29466409
http://dx.doi.org/10.1371/journal.pone.0192304

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