Loss of HCN2 leads to delayed gastrointestinal motility and reduced energy intake in mice

Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channels are important regulators of excitability in neural, cardiac, and other pacemaking cells, which are often altered in disease. In mice, loss of HCN2 leads to cardiac dysrhythmias, persistent spike-wave discharges similar to those seen...

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Detalles Bibliográficos
Autores principales: Fisher, Daniel W., Luu, Phillip, Agarwal, Neha, Kurz, Jonathan E., Chetkovich, Dane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821371/
https://www.ncbi.nlm.nih.gov/pubmed/29466436
http://dx.doi.org/10.1371/journal.pone.0193012

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