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UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer

Defects in mitosis can lead to aneuploidy, which is a common feature of human cancers. Spindle Assembly Checkpoint (SAC) controls fidelity of chromosome segregation in mitosis to prevent aneuploidy. The ubiquitin receptor protein Ubiquitin Associated and SH3 Domain Containing B (UBASH3B) was recentl...

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Detalles Bibliográficos
Autores principales:	Krupina, Ksenia, Kleiss, Charlotte, Awal, Sushil, Rodriguez-Hernandez, Irene, Sanz-Moreno, Victoria, Sumara, Izabela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Short Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821415/ https://www.ncbi.nlm.nih.gov/pubmed/29487893 http://dx.doi.org/10.1080/23723556.2016.1271494

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