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Untargeted metabolomics reveals distinct metabolic reprogramming in endothelial cells co-cultured with CSC and non-CSC prostate cancer cell subpopulations
Tumour angiogenesis is an important hallmark of cancer and the study of its metabolic adaptations, downstream to any cellular change, can reveal attractive targets for inhibiting cancer growth. In the tumour microenvironment, endothelial cells (ECs) interact with heterogeneous tumour cell types that...
Autores principales: | Jayaraman, Anusha, Kumar, Praveen, Marin, Silvia, de Atauri, Pedro, Mateo, Francesca, M. Thomson, Timothy, J. Centelles, Josep, F. Graham, Stewart, Cascante, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821452/ https://www.ncbi.nlm.nih.gov/pubmed/29466368 http://dx.doi.org/10.1371/journal.pone.0192175 |
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