Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin–EGFR crosstalk

Hereditary diffuse gastric cancer is a cancer predisposition syndrome associated with germline mutations of the E-cadherin gene (CDH1; NM_004360). Male CDH1 germline mutation carriers have by the age of 80 years an estimated 70% cumulative incidence of gastric cancer, females of 56% for gastric and...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Lo, Winifred, Rudloff, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821620/
https://www.ncbi.nlm.nih.gov/pubmed/29468433
http://dx.doi.org/10.1186/s40169-018-0184-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821620/
https://www.ncbi.nlm.nih.gov/pubmed/29468433
http://dx.doi.org/10.1186/s40169-018-0184-7

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