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Enhancing Hi-C data resolution with deep convolutional neural network HiCPlus

Although Hi-C technology is one of the most popular tools for studying 3D genome organization, due to sequencing cost, the resolution of most Hi-C datasets are coarse and cannot be used to link distal regulatory elements to their target genes. Here we develop HiCPlus, a computational approach based...

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Detalles Bibliográficos
Autores principales:	Zhang, Yan, An, Lin, Xu, Jie, Zhang, Bo, Zheng, W. Jim, Hu, Ming, Tang, Jijun, Yue, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821732/ https://www.ncbi.nlm.nih.gov/pubmed/29467363 http://dx.doi.org/10.1038/s41467-018-03113-2

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