Effector CD4(+) T cells recognize intravascular antigen presented by patrolling monocytes

Although effector CD4(+) T cells readily respond to antigen outside the vasculature, how they respond to intravascular antigens is unknown. Here we show the process of intravascular antigen recognition using intravital multiphoton microscopy of glomeruli. CD4(+) T cells undergo intravascular migrati...

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Detalles Bibliográficos
Autores principales: Westhorpe, Clare L. V., Norman, M. Ursula, Hall, Pam, Snelgrove, Sarah L., Finsterbusch, Michaela, Li, Anqi, Lo, Camden, Tan, Zhe Hao, Li, Songhui, Nilsson, Susan K., Kitching, A. Richard, Hickey, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821889/
https://www.ncbi.nlm.nih.gov/pubmed/29467472
http://dx.doi.org/10.1038/s41467-018-03181-4

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