Cargando…
Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly amongst IspD/IspE/IspF enzymes in the MEP pathway
2-C-Methyl-d-erythritol 2,4-cyclodiphosphate synthase (IspF) is a key enzyme in the 2-C-Methyl-d-erythritol-4-phosphate (MEP) pathway of isoprenoid biosynthesis. This enzyme catalyzes the 4-diphosphocytidyl-2-C-methyl-d-erythritol 2-phosphate (CDPME2P) to 2-C-methyl-d-erythritol 2,4-cyclodiphosphate...
Autores principales: | Liu, Zhongchuan, Jin, Yun, Liu, Weifeng, Tao, Yong, Wang, Ganggang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821942/ https://www.ncbi.nlm.nih.gov/pubmed/29335298 http://dx.doi.org/10.1042/BSR20171370 |
Ejemplares similares
-
Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment
por: O’Rourke, Patrick EF, et al.
Publicado: (2014) -
A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis
por: Jin, Yun, et al.
Publicado: (2016) -
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
por: Diamanti, Eleonora, et al.
Publicado: (2022) -
Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactor
por: Root, Katharina, et al.
Publicado: (2018) -
ISP shining !!!
por: Mathur, Lalit Kumar
Publicado: (2011)