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Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity

OBJECTIVES: To compare the effectiveness of the topical administration of benzocaine and EMLA on oral pain and tactile sensitivity. MATERIALS AND METHODS: A randomized, double-blind, split-mouth clinical trial was carried out with 20 volunteers. The sensorial and quantitative tests were applied befo...

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Autores principales: Gondim, David Gomes de Alencar, Montagner, Antonio Marcos, Pita-Neto, Ivo Cavalcante, Bringel, Romildo José de Siqueira, Sandrini, Francisco Aurelio Luchesi, Moreno, Eduardo Fernando Chaves, de Sousa, Amanda Mendes, Correia, Andreza Bastos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821963/
https://www.ncbi.nlm.nih.gov/pubmed/29593794
http://dx.doi.org/10.1155/2018/7916274
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author Gondim, David Gomes de Alencar
Montagner, Antonio Marcos
Pita-Neto, Ivo Cavalcante
Bringel, Romildo José de Siqueira
Sandrini, Francisco Aurelio Luchesi
Moreno, Eduardo Fernando Chaves
de Sousa, Amanda Mendes
Correia, Andreza Bastos
author_facet Gondim, David Gomes de Alencar
Montagner, Antonio Marcos
Pita-Neto, Ivo Cavalcante
Bringel, Romildo José de Siqueira
Sandrini, Francisco Aurelio Luchesi
Moreno, Eduardo Fernando Chaves
de Sousa, Amanda Mendes
Correia, Andreza Bastos
author_sort Gondim, David Gomes de Alencar
collection PubMed
description OBJECTIVES: To compare the effectiveness of the topical administration of benzocaine and EMLA on oral pain and tactile sensitivity. MATERIALS AND METHODS: A randomized, double-blind, split-mouth clinical trial was carried out with 20 volunteers. The sensorial and quantitative tests were applied before the contact with topical anesthetic and after the application. RESULTS: In the superficial tactile perception test, when we compared each group singly, there were statistically significant values in the decrease of superficial tactile perception when compared to the moment prior to the application of anesthetic agents. For the sensitivity to mechanical pain, no statistical significant difference was observed at evaluated times. In the needle penetration test, in an intergroup analysis, we found a decrease in the pain sensitivity to needle penetration at 5 min (p=0.053) and at 10 min (p=0.019) after the contact of the anesthetic drug with the oral mucosa. CONCLUSION: The application of topical anesthetic drugs reduces the discomfort associated with this procedure, mainly until the first 10 minutes. Only the needle penetration sensitivity test showed sufficient sensitivity to reveal a difference in the anesthetic effect between EMLA and benzocaine. This trial is registered with RBR-2N2GSW.
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spelling pubmed-58219632018-03-28 Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity Gondim, David Gomes de Alencar Montagner, Antonio Marcos Pita-Neto, Ivo Cavalcante Bringel, Romildo José de Siqueira Sandrini, Francisco Aurelio Luchesi Moreno, Eduardo Fernando Chaves de Sousa, Amanda Mendes Correia, Andreza Bastos Int J Dent Clinical Study OBJECTIVES: To compare the effectiveness of the topical administration of benzocaine and EMLA on oral pain and tactile sensitivity. MATERIALS AND METHODS: A randomized, double-blind, split-mouth clinical trial was carried out with 20 volunteers. The sensorial and quantitative tests were applied before the contact with topical anesthetic and after the application. RESULTS: In the superficial tactile perception test, when we compared each group singly, there were statistically significant values in the decrease of superficial tactile perception when compared to the moment prior to the application of anesthetic agents. For the sensitivity to mechanical pain, no statistical significant difference was observed at evaluated times. In the needle penetration test, in an intergroup analysis, we found a decrease in the pain sensitivity to needle penetration at 5 min (p=0.053) and at 10 min (p=0.019) after the contact of the anesthetic drug with the oral mucosa. CONCLUSION: The application of topical anesthetic drugs reduces the discomfort associated with this procedure, mainly until the first 10 minutes. Only the needle penetration sensitivity test showed sufficient sensitivity to reveal a difference in the anesthetic effect between EMLA and benzocaine. This trial is registered with RBR-2N2GSW. Hindawi 2018-02-07 /pmc/articles/PMC5821963/ /pubmed/29593794 http://dx.doi.org/10.1155/2018/7916274 Text en Copyright © 2018 David Gomes de Alencar Gondim et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Gondim, David Gomes de Alencar
Montagner, Antonio Marcos
Pita-Neto, Ivo Cavalcante
Bringel, Romildo José de Siqueira
Sandrini, Francisco Aurelio Luchesi
Moreno, Eduardo Fernando Chaves
de Sousa, Amanda Mendes
Correia, Andreza Bastos
Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity
title Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity
title_full Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity
title_fullStr Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity
title_full_unstemmed Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity
title_short Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA(®) on Oral Pain and Tactile Sensitivity
title_sort comparative analysis of the effectiveness of the topical administration of benzocaine and emla(®) on oral pain and tactile sensitivity
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821963/
https://www.ncbi.nlm.nih.gov/pubmed/29593794
http://dx.doi.org/10.1155/2018/7916274
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