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A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy

We report an aggressive case of polymicrobial bacteremia in a patient with renal pelvis carcinoma. A 76-year-old man developed watery diarrhea after undergoing chemotherapy. He became unconscious and went into shock. Laboratory data showed severe neutropenia, renal failure, and lactic acidosis. Ches...

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Autores principales: Arahata, Kyoko, Yamaguchi, Ryo, Terashima, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821991/
https://www.ncbi.nlm.nih.gov/pubmed/29593918
http://dx.doi.org/10.1155/2018/4165960
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author Arahata, Kyoko
Yamaguchi, Ryo
Terashima, Takeshi
author_facet Arahata, Kyoko
Yamaguchi, Ryo
Terashima, Takeshi
author_sort Arahata, Kyoko
collection PubMed
description We report an aggressive case of polymicrobial bacteremia in a patient with renal pelvis carcinoma. A 76-year-old man developed watery diarrhea after undergoing chemotherapy. He became unconscious and went into shock. Laboratory data showed severe neutropenia, renal failure, and lactic acidosis. Chest radiography showed multiple opacities. He died despite aggressive fluid resuscitation, catecholamine administration, antibiotic treatment, and mechanical ventilation. Blood culture isolates included Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, Acinetobacter baumannii, and Moraxella catarrhalis. The foci of bacteremia were the respiratory tract and the bowel. The two infection foci and polymicrobial bacteremia are thought to be associated with the patient's poor prognosis. Although polymicrobial bacteremia is rare, awareness of this condition and of the rare causative pathogens, such as A. baumannii and M. catarrhalis, especially in patients with comorbidities and immunosuppression will help treat the patients with bacteremia.
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spelling pubmed-58219912018-03-28 A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy Arahata, Kyoko Yamaguchi, Ryo Terashima, Takeshi Case Rep Infect Dis Case Report We report an aggressive case of polymicrobial bacteremia in a patient with renal pelvis carcinoma. A 76-year-old man developed watery diarrhea after undergoing chemotherapy. He became unconscious and went into shock. Laboratory data showed severe neutropenia, renal failure, and lactic acidosis. Chest radiography showed multiple opacities. He died despite aggressive fluid resuscitation, catecholamine administration, antibiotic treatment, and mechanical ventilation. Blood culture isolates included Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, Acinetobacter baumannii, and Moraxella catarrhalis. The foci of bacteremia were the respiratory tract and the bowel. The two infection foci and polymicrobial bacteremia are thought to be associated with the patient's poor prognosis. Although polymicrobial bacteremia is rare, awareness of this condition and of the rare causative pathogens, such as A. baumannii and M. catarrhalis, especially in patients with comorbidities and immunosuppression will help treat the patients with bacteremia. Hindawi 2018-01-15 /pmc/articles/PMC5821991/ /pubmed/29593918 http://dx.doi.org/10.1155/2018/4165960 Text en Copyright © 2018 Kyoko Arahata et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Arahata, Kyoko
Yamaguchi, Ryo
Terashima, Takeshi
A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy
title A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy
title_full A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy
title_fullStr A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy
title_full_unstemmed A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy
title_short A Case of Polymicrobial Bacteremia in a Patient Undergoing Chemotherapy
title_sort case of polymicrobial bacteremia in a patient undergoing chemotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821991/
https://www.ncbi.nlm.nih.gov/pubmed/29593918
http://dx.doi.org/10.1155/2018/4165960
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