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A unified approach for quantifying and interpreting DNA shape readout by transcription factors

Transcription factors (TFs) interpret DNA sequence by probing the chemical and structural properties of the nucleotide polymer. DNA shape is thought to enable a parsimonious representation of dependencies between nucleotide positions. Here, we propose a unified mathematical representation of the DNA...

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Detalles Bibliográficos
Autores principales:	Rube, H Tomas, Rastogi, Chaitanya, Kribelbauer, Judith F, Bussemaker, Harmen J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822049/ https://www.ncbi.nlm.nih.gov/pubmed/29472273 http://dx.doi.org/10.15252/msb.20177902

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