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Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines

[Image: see text] Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazoli...

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Autores principales: Riesco-Domínguez, Alejandra, van de Wiel, Jeroen, Hamlin, Trevor A., van Beek, Bas, Lindell, Stephen D., Blanco-Ania, Daniel, Bickelhaupt, F. Matthias, Rutjes, Floris P. J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822222/
https://www.ncbi.nlm.nih.gov/pubmed/29320179
http://dx.doi.org/10.1021/acs.joc.7b02639
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author Riesco-Domínguez, Alejandra
van de Wiel, Jeroen
Hamlin, Trevor A.
van Beek, Bas
Lindell, Stephen D.
Blanco-Ania, Daniel
Bickelhaupt, F. Matthias
Rutjes, Floris P. J. T.
author_facet Riesco-Domínguez, Alejandra
van de Wiel, Jeroen
Hamlin, Trevor A.
van Beek, Bas
Lindell, Stephen D.
Blanco-Ania, Daniel
Bickelhaupt, F. Matthias
Rutjes, Floris P. J. T.
author_sort Riesco-Domínguez, Alejandra
collection PubMed
description [Image: see text] Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines.
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spelling pubmed-58222222018-02-26 Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines Riesco-Domínguez, Alejandra van de Wiel, Jeroen Hamlin, Trevor A. van Beek, Bas Lindell, Stephen D. Blanco-Ania, Daniel Bickelhaupt, F. Matthias Rutjes, Floris P. J. T. J Org Chem [Image: see text] Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines. American Chemical Society 2018-01-10 2018-02-16 /pmc/articles/PMC5822222/ /pubmed/29320179 http://dx.doi.org/10.1021/acs.joc.7b02639 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Riesco-Domínguez, Alejandra
van de Wiel, Jeroen
Hamlin, Trevor A.
van Beek, Bas
Lindell, Stephen D.
Blanco-Ania, Daniel
Bickelhaupt, F. Matthias
Rutjes, Floris P. J. T.
Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines
title Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines
title_full Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines
title_fullStr Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines
title_full_unstemmed Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines
title_short Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF(3)S-Containing Isoxazolidines
title_sort trifluoromethyl vinyl sulfide: a building block for the synthesis of cf(3)s-containing isoxazolidines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822222/
https://www.ncbi.nlm.nih.gov/pubmed/29320179
http://dx.doi.org/10.1021/acs.joc.7b02639
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