Gene deficiency and pharmacological inhibition of caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs

Both inflammatory processes and glutamatergic systems have been implicated in the pathophysiology of mood-related disorders. However, the role of caspase-1, a classic inflammatory caspase, in behavioral responses to chronic stress remains largely unknown. To address this issue, we examined the effec...

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Detalles Bibliográficos
Autores principales: Li, M-X, Zheng, H-L, Luo, Y, He, J-G, Wang, W, Han, J, Zhang, L, Wang, X, Ni, L, Zhou, H-Y, Hu, Z-L, Wu, P-F, Jin, Y, Long, L-H, Zhang, H, Hu, G, Chen, J-G, Wang, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822452/
https://www.ncbi.nlm.nih.gov/pubmed/28416811
http://dx.doi.org/10.1038/mp.2017.76

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