Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood

Single-nucleotide polymorphisms (SNPs) in CACNA1C, the α1C subunit of the voltage-gated L-type calcium channel Ca(v)1.2, rank among the most consistent and replicable genetics findings in psychiatry and have been associated with schizophrenia, bipolar disorder and major depression. However, genetic...

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Detalles Bibliográficos
Autores principales: Dedic, N, Pöhlmann, M L, Richter, J S, Mehta, D, Czamara, D, Metzger, M W, Dine, J, Bedenk, B T, Hartmann, J, Wagner, K V, Jurik, A, Almli, L M, Lori, A, Moosmang, S, Hofmann, F, Wotjak, C T, Rammes, G, Eder, M, Chen, A, Ressler, K J, Wurst, W, Schmidt, M V, Binder, E B, Deussing, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822460/
https://www.ncbi.nlm.nih.gov/pubmed/28696432
http://dx.doi.org/10.1038/mp.2017.133

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