Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects

Several preclinical studies have reported the rapid antidepressant effects of N-methyl-D-aspartate receptor (NMDAR) antagonists, although the underlying mechanisms are still unclear. Death-associated protein kinase 1 (DAPK1) couples GluN2B subunits at extrasynaptic sites to regulate NMDAR channel co...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, S-X, Han, Y, Xu, L-Z, Yuan, K, Zhang, R-X, Sun, C-Y, Xu, D-F, Yuan, M, Deng, J-H, Meng, S-Q, Gao, X-J, Wen, Q, Liu, L-J, Zhu, W-L, Xue, Y-X, Zhao, M, Shi, J, Lu, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822462/
https://www.ncbi.nlm.nih.gov/pubmed/28439098
http://dx.doi.org/10.1038/mp.2017.85

Ejemplares similares

Ejemplares similares