Efficacy of different DNA and MVA prime-boost vaccination regimens against a Rift Valley fever virus (RVFV) challenge in sheep 12 weeks following vaccination

The aim of this work was to evaluate the immunogenicity and efficacy of DNA and MVA vaccines encoding the RVFV glycoproteins Gn and Gc in an ovine model of RVFV infection. Adult sheep of both sexes were challenged 12 weeks after the last immunization and clinical, virological, biochemical and immuno...

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Detalles Bibliográficos
Autores principales: Lorenzo, Gema, López-Gil, Elena, Ortego, Javier, Brun, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822472/
https://www.ncbi.nlm.nih.gov/pubmed/29467018
http://dx.doi.org/10.1186/s13567-018-0516-z

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