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Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

BACKGROUND: The methylation status of oxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter has been associated with treatment response in glioblastoma(GBM). Using pre-operative MRI techniques to predict MGMT promoter methylation status remains inconclusive. In this study, we investigated the...

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Detalles Bibliográficos
Autores principales: Han, Yu, Yan, Lin-Feng, Wang, Xi-Bin, Sun, Ying-Zhi, Zhang, Xin, Liu, Zhi-Cheng, Nan, Hai-Yan, Hu, Yu-Chuan, Yang, Yang, Zhang, Jin, Yu, Ying, Sun, Qian, Tian, Qiang, Hu, Bo, Xiao, Gang, Wang, Wen, Cui, Guang-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822523/
https://www.ncbi.nlm.nih.gov/pubmed/29467012
http://dx.doi.org/10.1186/s12885-018-4114-2