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Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

BACKGROUND: Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D), although the precise mechanisms underlying the relationship remain unknown. In this study we identified alterations of DNA methylation influencing T2D pathogenesis, in subcutaneous and visceral adi...

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Detalles Bibliográficos
Autores principales: Barajas-Olmos, Francisco, Centeno-Cruz, Federico, Zerrweck, Carlos, Imaz-Rosshandler, Iván, Martínez-Hernández, Angélica, Cordova, Emilio J., Rangel-Escareño, Claudia, Gálvez, Faustino, Castillo, Armando, Maydón, Hernán, Campos, Francisco, Maldonado-Pintado, Diana Gabriela, Orozco, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822594/
https://www.ncbi.nlm.nih.gov/pubmed/29466957
http://dx.doi.org/10.1186/s12881-018-0542-8

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