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Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes
BACKGROUND: Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D), although the precise mechanisms underlying the relationship remain unknown. In this study we identified alterations of DNA methylation influencing T2D pathogenesis, in subcutaneous and visceral adi...
Autores principales: | Barajas-Olmos, Francisco, Centeno-Cruz, Federico, Zerrweck, Carlos, Imaz-Rosshandler, Iván, Martínez-Hernández, Angélica, Cordova, Emilio J., Rangel-Escareño, Claudia, Gálvez, Faustino, Castillo, Armando, Maydón, Hernán, Campos, Francisco, Maldonado-Pintado, Diana Gabriela, Orozco, Lorena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822594/ https://www.ncbi.nlm.nih.gov/pubmed/29466957 http://dx.doi.org/10.1186/s12881-018-0542-8 |
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