The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

BACKGROUND: MYCN is amplified in small cell lung cancers and several pediatric tumors, including alveolar rhabdomyosarcomas and neuroblastomas. MYCN protein is known to play a key oncogenic role in both alveolar rhabdomyosarcomas and neuroblastomas. MYCN opposite strand (MYCNOS) is a gene located on...

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Detalles Bibliográficos
Autores principales: O’Brien, Eleanor M., Selfe, Joanna L., Martins, Ana Sofia, Walters, Zoë S., Shipley, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822637/
https://www.ncbi.nlm.nih.gov/pubmed/29466962
http://dx.doi.org/10.1186/s12885-018-4129-8

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