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The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan

BACKGROUND: Peripheral neuropathy is one of the most common microvascular complication of diabetes mellitus. This study is conducted to determine the prevalence of diabetic peripheral neuropathy (DPN) and its associated factors among patients with type 2 diabetes mellitus in Jordan. METHODS: A cross...

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Autores principales: Khawaja, Nahla, Abu-Shennar, Jawad, Saleh, Mohammed, Dahbour, Said S., Khader, Yousef S., Ajlouni, Kamel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822644/
https://www.ncbi.nlm.nih.gov/pubmed/29483946
http://dx.doi.org/10.1186/s13098-018-0309-6
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author Khawaja, Nahla
Abu-Shennar, Jawad
Saleh, Mohammed
Dahbour, Said S.
Khader, Yousef S.
Ajlouni, Kamel M.
author_facet Khawaja, Nahla
Abu-Shennar, Jawad
Saleh, Mohammed
Dahbour, Said S.
Khader, Yousef S.
Ajlouni, Kamel M.
author_sort Khawaja, Nahla
collection PubMed
description BACKGROUND: Peripheral neuropathy is one of the most common microvascular complication of diabetes mellitus. This study is conducted to determine the prevalence of diabetic peripheral neuropathy (DPN) and its associated factors among patients with type 2 diabetes mellitus in Jordan. METHODS: A cross-sectional study was conducted at the National Center for Diabetes, Endocrinology and Genetics, Jordan. A total of 1003 patients with type 2 diabetes were recruited. Data were collected from participants during a face-to-face structured interview. DPN was assessed using the translated version of Michigan Neuropathy Screening Instrument (MNSI). RESULTS: The overall prevalence of DPN based on MNSI was 39.5%. The most frequently reported symptoms were numbness (32.3%) and pain with walking (29.7%), while the least reported symptoms were the history of amputation (1.3%) and loss of sensation in legs/feet while walking (3.8%). Logistic regression analysis revealed that unemployment, cardiovascular disease, dyslipidemia, diabetic retinopathy and long standing DM (diabetes of ≥ 5 years) were significantly associated with DPN. CONCLUSION: Peripheral Neuropathy is highly prevalent among Jordanian patients with type 2 diabetes mellitus. DPN was significantly associated with duration of DM, dyslipidemia, diabetic retinopathy, cardiovascular disease, and unemployment. Early detection and appropriate intervention are mandatory among high-risk groups.
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spelling pubmed-58226442018-02-26 The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan Khawaja, Nahla Abu-Shennar, Jawad Saleh, Mohammed Dahbour, Said S. Khader, Yousef S. Ajlouni, Kamel M. Diabetol Metab Syndr Research BACKGROUND: Peripheral neuropathy is one of the most common microvascular complication of diabetes mellitus. This study is conducted to determine the prevalence of diabetic peripheral neuropathy (DPN) and its associated factors among patients with type 2 diabetes mellitus in Jordan. METHODS: A cross-sectional study was conducted at the National Center for Diabetes, Endocrinology and Genetics, Jordan. A total of 1003 patients with type 2 diabetes were recruited. Data were collected from participants during a face-to-face structured interview. DPN was assessed using the translated version of Michigan Neuropathy Screening Instrument (MNSI). RESULTS: The overall prevalence of DPN based on MNSI was 39.5%. The most frequently reported symptoms were numbness (32.3%) and pain with walking (29.7%), while the least reported symptoms were the history of amputation (1.3%) and loss of sensation in legs/feet while walking (3.8%). Logistic regression analysis revealed that unemployment, cardiovascular disease, dyslipidemia, diabetic retinopathy and long standing DM (diabetes of ≥ 5 years) were significantly associated with DPN. CONCLUSION: Peripheral Neuropathy is highly prevalent among Jordanian patients with type 2 diabetes mellitus. DPN was significantly associated with duration of DM, dyslipidemia, diabetic retinopathy, cardiovascular disease, and unemployment. Early detection and appropriate intervention are mandatory among high-risk groups. BioMed Central 2018-02-21 /pmc/articles/PMC5822644/ /pubmed/29483946 http://dx.doi.org/10.1186/s13098-018-0309-6 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Khawaja, Nahla
Abu-Shennar, Jawad
Saleh, Mohammed
Dahbour, Said S.
Khader, Yousef S.
Ajlouni, Kamel M.
The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan
title The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan
title_full The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan
title_fullStr The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan
title_full_unstemmed The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan
title_short The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan
title_sort prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of jordan
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822644/
https://www.ncbi.nlm.nih.gov/pubmed/29483946
http://dx.doi.org/10.1186/s13098-018-0309-6
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