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Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study

OBJECTIVES: Cage design and material properties play a crucial role in the long-term results, since interbody fusions using intervertebral cages have become one of the basic procedures in spinal surgery. Our aim is to design a novel Apatite-Wollastonite interbody fusion cage and evaluate its biomech...

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Autores principales: Bozkurt, Celal, Şenköylü, Alpaslan, Aktaş, Erdem, Sarıkaya, Baran, Sipahioğlu, Serkan, Gürbüz, Rıza, Timuçin, Muharrem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822753/
https://www.ncbi.nlm.nih.gov/pubmed/29581974
http://dx.doi.org/10.1155/2018/4152543
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author Bozkurt, Celal
Şenköylü, Alpaslan
Aktaş, Erdem
Sarıkaya, Baran
Sipahioğlu, Serkan
Gürbüz, Rıza
Timuçin, Muharrem
author_facet Bozkurt, Celal
Şenköylü, Alpaslan
Aktaş, Erdem
Sarıkaya, Baran
Sipahioğlu, Serkan
Gürbüz, Rıza
Timuçin, Muharrem
author_sort Bozkurt, Celal
collection PubMed
description OBJECTIVES: Cage design and material properties play a crucial role in the long-term results, since interbody fusions using intervertebral cages have become one of the basic procedures in spinal surgery. Our aim is to design a novel Apatite-Wollastonite interbody fusion cage and evaluate its biomechanical behavior in silico in a segmental spinal model. MATERIALS AND METHODS: Mechanical properties for the Apatite-Wollastonite bioceramic cages were obtained by fitting finite element results to the experimental compression behavior of a cage prototype. The prototype was made from hydroxyapatite, pseudowollastonite, and frit by sintering. The elastic modulus of the material was found to be 32 GPa. Three intact lumbar vertebral segments were modelled with the ANSYS 12.0.1 software and this model was modified to simulate a Posterior Lumbar Interbody Fusion. Four cage designs in different geometries were analyzed in silico under axial loading, flexion, extension, and lateral bending. RESULTS: The K2 design had the best overall biomechanical performance for the loads considered. Maximum cage stress recorded was 36.7 MPa in compression after a flexion load, which was within the biomechanical limits of the cage. CONCLUSION: Biomechanical analyses suggest that K2 bioceramic cage is an optimal design and reveals essential material properties for a stable interbody fusion.
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spelling pubmed-58227532018-03-26 Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study Bozkurt, Celal Şenköylü, Alpaslan Aktaş, Erdem Sarıkaya, Baran Sipahioğlu, Serkan Gürbüz, Rıza Timuçin, Muharrem Biomed Res Int Research Article OBJECTIVES: Cage design and material properties play a crucial role in the long-term results, since interbody fusions using intervertebral cages have become one of the basic procedures in spinal surgery. Our aim is to design a novel Apatite-Wollastonite interbody fusion cage and evaluate its biomechanical behavior in silico in a segmental spinal model. MATERIALS AND METHODS: Mechanical properties for the Apatite-Wollastonite bioceramic cages were obtained by fitting finite element results to the experimental compression behavior of a cage prototype. The prototype was made from hydroxyapatite, pseudowollastonite, and frit by sintering. The elastic modulus of the material was found to be 32 GPa. Three intact lumbar vertebral segments were modelled with the ANSYS 12.0.1 software and this model was modified to simulate a Posterior Lumbar Interbody Fusion. Four cage designs in different geometries were analyzed in silico under axial loading, flexion, extension, and lateral bending. RESULTS: The K2 design had the best overall biomechanical performance for the loads considered. Maximum cage stress recorded was 36.7 MPa in compression after a flexion load, which was within the biomechanical limits of the cage. CONCLUSION: Biomechanical analyses suggest that K2 bioceramic cage is an optimal design and reveals essential material properties for a stable interbody fusion. Hindawi 2018-01-18 /pmc/articles/PMC5822753/ /pubmed/29581974 http://dx.doi.org/10.1155/2018/4152543 Text en Copyright © 2018 Celal Bozkurt et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bozkurt, Celal
Şenköylü, Alpaslan
Aktaş, Erdem
Sarıkaya, Baran
Sipahioğlu, Serkan
Gürbüz, Rıza
Timuçin, Muharrem
Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study
title Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study
title_full Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study
title_fullStr Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study
title_full_unstemmed Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study
title_short Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study
title_sort biomechanical evaluation of a novel apatite-wollastonite ceramic cage design for lumbar interbody fusion: a finite element model study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822753/
https://www.ncbi.nlm.nih.gov/pubmed/29581974
http://dx.doi.org/10.1155/2018/4152543
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