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Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling

INTRODUCTION: DPP4 inhibitors (gliptins) are commonly used antidiabetic drugs for the treatment of type 2 diabetes. Gliptins also act in a glucose-independent manner and show vasoregenerative effects. We have shown that gliptins can remarkably accelerate vascular healing after vascular injury. Howev...

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Detalles Bibliográficos
Autores principales: Remm, Friederike, Kränkel, Nicolle, Lener, Daniela, Drucker, Daniel J., Sopper, Sieghart, Brenner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822806/
https://www.ncbi.nlm.nih.gov/pubmed/29531541
http://dx.doi.org/10.1155/2018/5284963