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A new era of thromboelastometry

Severe hemorrhage with necessity of allogeneic blood transfusion is common complication in intensive care unit and is associated with increased morbidity and mortality. Prompt recognition and treatment of bleeding causes becomes essential for the effective control of hemorrhage, rationalizing the us...

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Autores principales: Crochemore, Tomaz, Piza, Felipe Maia de Toledo, Rodrigues, Roseny dos Reis, Guerra, João Carlos de Campos, Ferraz, Leonardo José Rolim, Corrêa, Thiago Domingos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823059/
https://www.ncbi.nlm.nih.gov/pubmed/28614427
http://dx.doi.org/10.1590/S1679-45082017MD3130
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author Crochemore, Tomaz
Piza, Felipe Maia de Toledo
Rodrigues, Roseny dos Reis
Guerra, João Carlos de Campos
Ferraz, Leonardo José Rolim
Corrêa, Thiago Domingos
author_facet Crochemore, Tomaz
Piza, Felipe Maia de Toledo
Rodrigues, Roseny dos Reis
Guerra, João Carlos de Campos
Ferraz, Leonardo José Rolim
Corrêa, Thiago Domingos
author_sort Crochemore, Tomaz
collection PubMed
description Severe hemorrhage with necessity of allogeneic blood transfusion is common complication in intensive care unit and is associated with increased morbidity and mortality. Prompt recognition and treatment of bleeding causes becomes essential for the effective control of hemorrhage, rationalizing the use of allogeneic blood components, and in this way, preventing an occurrence of their potential adverse effects. Conventional coagulation tests such as prothrombin time and activated partial thromboplastin time present limitations in predicting bleeding and guiding transfusion therapy in critically ill patients. Viscoelastic tests such as thromboelastography and rotational thromboelastometry allow rapid detection of coagulopathy and goal-directed therapy with specific hemostatic drugs. The new era of thromboelastometry relies on its efficacy, practicality, reproducibility and cost-effectiveness to establish itself as the main diagnostic tool and transfusion guide in patients with severe active bleeding.
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spelling pubmed-58230592018-02-23 A new era of thromboelastometry Crochemore, Tomaz Piza, Felipe Maia de Toledo Rodrigues, Roseny dos Reis Guerra, João Carlos de Campos Ferraz, Leonardo José Rolim Corrêa, Thiago Domingos Einstein (Sao Paulo) Medical Developments Severe hemorrhage with necessity of allogeneic blood transfusion is common complication in intensive care unit and is associated with increased morbidity and mortality. Prompt recognition and treatment of bleeding causes becomes essential for the effective control of hemorrhage, rationalizing the use of allogeneic blood components, and in this way, preventing an occurrence of their potential adverse effects. Conventional coagulation tests such as prothrombin time and activated partial thromboplastin time present limitations in predicting bleeding and guiding transfusion therapy in critically ill patients. Viscoelastic tests such as thromboelastography and rotational thromboelastometry allow rapid detection of coagulopathy and goal-directed therapy with specific hemostatic drugs. The new era of thromboelastometry relies on its efficacy, practicality, reproducibility and cost-effectiveness to establish itself as the main diagnostic tool and transfusion guide in patients with severe active bleeding. Instituto Israelita de Ensino e Pesquisa Albert Einstein 2017 /pmc/articles/PMC5823059/ /pubmed/28614427 http://dx.doi.org/10.1590/S1679-45082017MD3130 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Medical Developments
Crochemore, Tomaz
Piza, Felipe Maia de Toledo
Rodrigues, Roseny dos Reis
Guerra, João Carlos de Campos
Ferraz, Leonardo José Rolim
Corrêa, Thiago Domingos
A new era of thromboelastometry
title A new era of thromboelastometry
title_full A new era of thromboelastometry
title_fullStr A new era of thromboelastometry
title_full_unstemmed A new era of thromboelastometry
title_short A new era of thromboelastometry
title_sort new era of thromboelastometry
topic Medical Developments
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823059/
https://www.ncbi.nlm.nih.gov/pubmed/28614427
http://dx.doi.org/10.1590/S1679-45082017MD3130
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