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Dental Tissue — New Source for Stem Cells

Stem cells have been isolated from many tissues and organs, including dental tissue. Five types of dental stem cells have been established: dental pulp stem cells, stem cells from exfoliated deciduous teeth, stem cells from apical papilla, periodontal ligament stem cells, and dental follicle progeni...

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Detalles Bibliográficos
Autores principales: Petrovic, Vladimir, Stefanovic, Vladisav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823208/
https://www.ncbi.nlm.nih.gov/pubmed/19838602
http://dx.doi.org/10.1100/tsw.2009.125
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author Petrovic, Vladimir
Stefanovic, Vladisav
author_facet Petrovic, Vladimir
Stefanovic, Vladisav
author_sort Petrovic, Vladimir
collection PubMed
description Stem cells have been isolated from many tissues and organs, including dental tissue. Five types of dental stem cells have been established: dental pulp stem cells, stem cells from exfoliated deciduous teeth, stem cells from apical papilla, periodontal ligament stem cells, and dental follicle progenitor cells. The main characteristics of dental stem cells are their potential for multilineage differentiation and self-renewal capacity. Dental stem cells can differentiate into odontoblasts, adipocytes, neuronal-like cells, glial cells, osteoblasts, chondrocytes, melanocytes, myotubes, and endothelial cells. Possible application of these cells in various fields of medicine makes them good candidates for future research as a new, powerful tool for therapy. Although the possible use of these cells in therapeutic purposes and tooth tissue engineering is still in the beginning stages, the results are promising. The efforts made in the research of dental stem cells have clarified many mechanisms underlying the biological processes in which these cells are involved. This review will focus on the new findings in the field of dental stem cell research and on their potential use in the therapy of various disorders.
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spelling pubmed-58232082018-03-14 Dental Tissue — New Source for Stem Cells Petrovic, Vladimir Stefanovic, Vladisav ScientificWorldJournal Review Article Stem cells have been isolated from many tissues and organs, including dental tissue. Five types of dental stem cells have been established: dental pulp stem cells, stem cells from exfoliated deciduous teeth, stem cells from apical papilla, periodontal ligament stem cells, and dental follicle progenitor cells. The main characteristics of dental stem cells are their potential for multilineage differentiation and self-renewal capacity. Dental stem cells can differentiate into odontoblasts, adipocytes, neuronal-like cells, glial cells, osteoblasts, chondrocytes, melanocytes, myotubes, and endothelial cells. Possible application of these cells in various fields of medicine makes them good candidates for future research as a new, powerful tool for therapy. Although the possible use of these cells in therapeutic purposes and tooth tissue engineering is still in the beginning stages, the results are promising. The efforts made in the research of dental stem cells have clarified many mechanisms underlying the biological processes in which these cells are involved. This review will focus on the new findings in the field of dental stem cell research and on their potential use in the therapy of various disorders. TheScientificWorldJOURNAL 2009-10-14 /pmc/articles/PMC5823208/ /pubmed/19838602 http://dx.doi.org/10.1100/tsw.2009.125 Text en Copyright © 2009 Vladimir Petrovic and Vladisav Stefanovic. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Petrovic, Vladimir
Stefanovic, Vladisav
Dental Tissue — New Source for Stem Cells
title Dental Tissue — New Source for Stem Cells
title_full Dental Tissue — New Source for Stem Cells
title_fullStr Dental Tissue — New Source for Stem Cells
title_full_unstemmed Dental Tissue — New Source for Stem Cells
title_short Dental Tissue — New Source for Stem Cells
title_sort dental tissue — new source for stem cells
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823208/
https://www.ncbi.nlm.nih.gov/pubmed/19838602
http://dx.doi.org/10.1100/tsw.2009.125
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