Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia

Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance...

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Autores principales: Chernyaeva, Ekaterina, Rotkevich, Mikhail, Krasheninnikova, Ksenia, Yurchenko, Andrey, Vyazovaya, Anna, Mokrousov, Igor, Solovieva, Natalia, Zhuravlev, Viacheslav, Yablonsky, Piotr, O’Brien, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823328/
https://www.ncbi.nlm.nih.gov/pubmed/29460750
http://dx.doi.org/10.3201/eid2403.170151
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author Chernyaeva, Ekaterina
Rotkevich, Mikhail
Krasheninnikova, Ksenia
Yurchenko, Andrey
Vyazovaya, Anna
Mokrousov, Igor
Solovieva, Natalia
Zhuravlev, Viacheslav
Yablonsky, Piotr
O’Brien, Stephen J.
author_facet Chernyaeva, Ekaterina
Rotkevich, Mikhail
Krasheninnikova, Ksenia
Yurchenko, Andrey
Vyazovaya, Anna
Mokrousov, Igor
Solovieva, Natalia
Zhuravlev, Viacheslav
Yablonsky, Piotr
O’Brien, Stephen J.
author_sort Chernyaeva, Ekaterina
collection PubMed
description Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, pathogenicity, and drug resistance.
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spelling pubmed-58233282018-03-01 Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia Chernyaeva, Ekaterina Rotkevich, Mikhail Krasheninnikova, Ksenia Yurchenko, Andrey Vyazovaya, Anna Mokrousov, Igor Solovieva, Natalia Zhuravlev, Viacheslav Yablonsky, Piotr O’Brien, Stephen J. Emerg Infect Dis Dispatch Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, pathogenicity, and drug resistance. Centers for Disease Control and Prevention 2018-03 /pmc/articles/PMC5823328/ /pubmed/29460750 http://dx.doi.org/10.3201/eid2403.170151 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Chernyaeva, Ekaterina
Rotkevich, Mikhail
Krasheninnikova, Ksenia
Yurchenko, Andrey
Vyazovaya, Anna
Mokrousov, Igor
Solovieva, Natalia
Zhuravlev, Viacheslav
Yablonsky, Piotr
O’Brien, Stephen J.
Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia
title Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia
title_full Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia
title_fullStr Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia
title_full_unstemmed Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia
title_short Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia
title_sort whole-genome analysis of mycobacterium tuberculosis from patients with tuberculous spondylitis, russia
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823328/
https://www.ncbi.nlm.nih.gov/pubmed/29460750
http://dx.doi.org/10.3201/eid2403.170151
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