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Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein
Dengue virus (DENV) infection imposes enormous health and economic burden worldwide with no approved treatment. Several small molecules, including lovastatin, celgosivir, balapiravir and chloroquine have been tested for potential anti-dengue activity in clinical trials; none of these have demonstrat...
Autores principales: | Budigi, Yadunanda, Ong, Eugenia Z., Robinson, Luke N., Ong, Li Ching, Rowley, Kirk J., Winnett, Alexander, Tan, Hwee Cheng, Hobbie, Sven, Shriver, Zachary, Babcock, Gregory J., Alonso, Sylvie, Ooi, Eng Eong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823465/ https://www.ncbi.nlm.nih.gov/pubmed/29425203 http://dx.doi.org/10.1371/journal.pntd.0006209 |
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