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Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4(+) T cells expressing CD30

HIV-1-infected cells persist indefinitely despite the use of combination antiretroviral therapy (ART), and novel therapeutic strategies to target and purge residual infected cells in individuals on ART are urgently needed. Here, we demonstrate that CD4(+) T cell-associated HIV-1 RNA is often highly...

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Detalles Bibliográficos
Autores principales:	Hogan, Louise E., Vasquez, Joshua, Hobbs, Kristen S., Hanhauser, Emily, Aguilar-Rodriguez, Brandon, Hussien, Rajaa, Thanh, Cassandra, Gibson, Erica A., Carvidi, Alexander B., Smith, Louis C. B., Khan, Shahzada, Trapecar, Martin, Sanjabi, Shomyseh, Somsouk, Ma, Stoddart, Cheryl A., Kuritzkes, Daniel R., Deeks, Steven G., Henrich, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823470/ https://www.ncbi.nlm.nih.gov/pubmed/29470552 http://dx.doi.org/10.1371/journal.ppat.1006856

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